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Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1

Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling

Diabetic metabolic dysfunction, increased ROS, and chronic inflammation damage the vascular endothelium, promoting atherosclerosis through EC injury, vascular smooth muscle cell dysfunction, and platelet hyperactivity

We did observe some reduction in the number of T cells (both CD8 + and CD4 + ), but not NK cells, in the liver post-infection in KO relative to WT mice

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