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Background: Autoantibodies to GAD or GAD65 are linked to autoimmune neurological syndromes, including stiff person syndrome (SPS), cerebellar ataxia, and epilepsy [1]

Peer review Peer review information Nature Reviews Methods Primers thanks Jeff Bulte, Bryan Smith, Yapei Zhang and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

These treatments work by removing dead skin cells, promoting cell turnover, and evening out skin tone

The N-terminal tails of these histones undergo various modifications-acetylation, phosphorylation, methylation, and ubiquitinationthat affect their interaction with DNA, thereby altering chromatin structure and regulating gene expression 15,88