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Carter BZ, Mak PY, Ke B, Nishida Y, Boettcher S, Bedoy A, Ostermann LB, DiNardo CD, Puzio-Kuter A, Levine A, Andreeff M

Jun 2007;68(2-3):113-7

Generally, M1 macrophages depend on glycolysis, while M2 macrophages are associated with oxidative phosphorylation and a metabolic state that involves fatty acid oxidation (FAO) [7, 8]

Adverse reactions leading to permanent discontinuation for patients receiving IBRANCE plus letrozole included neutropenia (1.1%) and alanine aminotransferase increase (0.7%)