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Consequently, targeting inflammation for resolution is regarded as a promising strategy for aging intervention 25

MOA: It is the most stable GHRH analog, providing a robust signal to the pituitary

10.1039/c5np00076a 89 RuanJ.YangM.FuP.YeY.LinG

Bergenin impedes the generation of extracellular matrix in glomerular mesangial cells and ameliorates diabetic nephropathy in mice by inhibiting oxidative stress via the mTOR/-TrcP/Nrf2 pathway

Both mitochondrial biogenesis and mitophagy increased with exercise, giving hepatocytes resilience to different stressors induced by NAFLD with increases in PGC1alpha, Tfam, Mfn1 and Mfn2 (Ghareghani et al., 2018[41]