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This BA-receptor signaling network does not operate in isolation

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Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms

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Nat Biotechnol 1990:8;27-32

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In several reported pediatric cases, ingestion of large amounts of alpha-lipoic acid (for example, 2400 mg in a toddler) led to serious reactions such as seizures, loss of consciousness, or metabolic acidosis

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