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Page 2 of a USEPA EtO fact sheet sent to communities ahead of informational meetings in Laredo, Texas, in 2022

Studies have shown that mtDNA can be detected in blood and cerebrospinal fluid post-TBI, providing a means to monitor injury severity and systemic inflammatory responses (Kayhanian et al., 2022)

ROS generated by mitochondria, particularly in response to cellular stress, act as signaling molecules that amplify necroptosis through promoting RIPK1/RIPK3/MLKL activation

Since vanillic acid has low bioavailability, and bioavailability of a compound depends (among other factors) on its chemical structure, testing isomers of vanillic acid may yield promising results