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The absorbance was measured at 450 nm (with reference wavelength 630 nm), and BH4 concentrations were calculated according to the standard curve

MenSCs exhibited superior cardioprotective effects and increased microvascular density, attributed to high miR-21 levels in their exosomes that activate the PTEN/Akt signaling pathway (Lopez-Verrilli et al., 2016)

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Silencing information regulator 1/Forkhead box O1-related signalling pathway Silencing information regulator 1 (SIRT1) is a key factor in helping cells defend against oxidative stress, and it plays an important role in maintaining the balance between bone formation and bone resorption [21, 58]