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Studies show that the levels of GPX4 mRNA and protein are significantly reduced in the hippocampus of CUMS mice, while the expression of PEBP1 is upregulated and the levels of Fe and Fe 2+ are notably increased

Crizotinib, a class Ia small molecule dual inhibitor of c-MET and anaplastic lymphoma kinase (ALK) had been proposed for advanced non-small cell lung cancer therapy with activation of either c-ros oncogene 1 (ROS-1) or ALK [110]

In this review, we provide insight into SARS-CoV-2 infection and intracellular host responses (targets, pathways, networks, biological processes, and functional adaptations) to viral invasion