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Botox and other botulinum toxin products like Dysport are formulated with complexing or accessory proteins

[PubMed] [Google Scholar] 50.Meister A

Collagen is the most abundant protein in the human body, and it decreases as we age, leading to the formation of wrinkles and fine lines

Retinoids still have decades of independent trials behind them

Initial research focused on its role in wound healing and tissue remodeling, where it was found to modulate the expression of extracellular matrix (ECM) proteins such as collagen and elastin