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As the body ages, the volume of glutathione decreases dramatically, allowing for exacerbated exposure to cellular oxidation and free radicals which cause visual skin aging

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Although this review focuses on inflammatory dermatoses that follow radiotherapy, we also warn of the long-term risk for secondary tumors in the irradiated field2 and for angiosarcoma in breast cancer patients who receive radiotherapy3 as well as risk for so-called atypical vascular lesions4 and acquired lymphangiectasis.5 Because many of these conditions are probably underdiagnosed or erroneously assumed to be more widely known syndromes like radiodermatitis, it is important to be aware of their individual clinical features

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4-Aza-3-oxo-5 alpha-androst-1-ene-17 beta-N-aryl-carboxamides as dual inhibitors of human type 1 and type 2 steroid 5 alpha-reductases