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Long-term cigarette smoke exposure increases uncoupling protein expression but reduces energy intake

Notably, patients with septic shock exhibit a significantly higher relative density of this modification

In a mouse model of cerebral ischemia, HCA2 activation by BHB promotes a neuroprotective phenotype of macrophages to produce prostaglandin D2, which exerts neuroprotective effects, suggesting a potential immunomodulatory mechanism that may be relevant in inflammatory contexts [45]

Biomed Eng Lett (2017) 7(2):5969

Among these, 3-hydroxylanosta-8,24-dien-21, trametenolic acid, and chagabusone A exhibited the most potent cytotoxicity against all human lung cancer cell lines tested, with EC 50 values ranging from 75.1 to 227.4 M