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The underlying reason for this toxicity is most likely because neuronal development and survival is based on BCL-XL activity (66)

Benign prostatic hyperplasia: pathogenesis and medical therapyJ

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Here, c-Fos expression in ARH AgRP neurons was measured after 24 h of fasting, while the importance of endogenous GH signaling in AgRP cells for the neuroendocrine responses to weight loss was evaluated in calorie-restricted mice that received 40% of their normal intake