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A subsequent screening process excluded 12 review articles and 32 studies deemed non-relevant based on their titles and abstracts

All xenobiotics, including free radicals, pathogens and heavy metals, like mercury, stick onto glutathione (the SH in GSH is the sulfur-hydrogen ion attached to the molecule ) and are then carried out of the body through bile and stool

The foundational 2012 paper reporting Dihexa's cognitive-enhancing effects received a formal expression of concern from the journal (PMID: 34551989), citing questions about data integrity including Western blot images

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[2] The MHRA Drug Safety Update (August 2022) advises healthcare professionals to consider testing vitamin B12 levels in patients taking metformin who develop symptoms of neuropathy or anaemia, and to consider periodic monitoring in those at risk of deficiency