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B.HammarstromC.FauskangerM.HaabethO

Serum ZAG concentration declines progressively with age, showing an inverse correlation with fasting blood glucose and triglyceride levels, while higher body mass index (BMI) is also negatively associated with ZAG levels [450]

On the other hand, NAC shows stronger reactivity towards hypochlorite and nitrogen dioxide, partially explaining its direct antioxidant effects against exogenous factors like diet, air pollution, or certain inflammatory conditions (Meyer et al., 1994

doi: 10.1016/S0140-6736(02)09839-2

Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management