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The monolayer was wounded with a 1,000-l pipette tip (Watson), washed with media and incubated in growth medium without rh EGF and with 0.25 nM hHGF or 100 nM dimeric macrocycles for 50 h

Unlike cisplatin and similarly to other antiarthritic gold drugs, auranofin appears to exert its activity through inhibition of enzyme activities rather than DNA damage