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In summary, monocyte-derived macrophages from individuals with CD have increased susceptibility to H 2 O 2 -induced ferroptosis cell death, that may be facilitated, at least in part, by reduced expression of the antioxidant GPx1

Dec 1 2018;128(1):75-84

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Injectable research studies have similarly reported low rates of adverse events, though this should not be read as a clinical endorsement for any particular use