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James OBrien, the condition may indicate an underlying life-threatening disease such as congestive heart failure, or it may be caused by something as benign as sitting for too long (OBrien 2005)

doi: 10.1016/j.eplepsyres.2005.03.008 96

Response of Male reproductive System against ionizing radiation and available radio-protective agents: cellular and molecular Insight

Structural requirements for the activation of rat anterior pituitary adenylate cyclase by growth hormone-releasing factor (GRF): discovery of ( N -Ac-Tyr 1 ,d-Arg 2 )-GRF(1-29)-NH 2 as a GRF antagonist on membranes

Initially studied for its role in promoting gut health, researchers discovered its extensive healing benefits beyond the gastrointestinal system