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There seems to be greater prevalence of androgen dysregulation in elite-level female athletes via polycystic ovarian syndrome (PCOS) [273,274,275,276], and in experimental settings, women show responsiveness to androgen supplementation in an age- and dose-dependent manner [277,278,279,280], supporting the hypothesis that androgens and AR play some role in modulating female body composition and muscle function

[DOI] [PubMed] [Google Scholar] [93].Hofstee BHJ, Immobilization of enzymes through non-covalent binding to substituted agaroses, Biochem