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Autism spectrum disorders and autistic traits: A decade of new twin studies

Regulation: Vitamin B12 deficiency leads to homocysteine accumulation, megaloblastic anemia and nerve injury

Risks of Use in Patients with Increased Intracranial Pressure, Brain Tumors, Head Injury, or Impaired Consciousness In patients who may be susceptible to the intracranial effects of CO2 retention (e.g., those with evidence of increased intracranial pressure or brain tumors), acetaminophen and codeine phosphate tablets may reduce respiratory drive, and the resultant CO2 retention can further increase intracranial pressure

It should be noted though, that inappropriate administration of folate when there is a vitamin B12 deficiency may cause neurologic and hematologic relapse (Reynolds, 2014)

These effects can potentially be achieved by both the administration of selected antioxidants such as vitamin E, vitamin C, or NAC, or after the consumption of food rich in nutraceutical compounds, which may show additive or synergistic effects