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Dietary B12 intakes affect serum holoTC concentrations with, as expected, lower levels in vegans than omnivores due to their lower B12 intake

Furthermore, individuals who have a sensitivity to cobalt-based substances should be careful when considering methylcobalamin as it could lead to reactions

Both have been studied in wound healing and musculoskeletal models, but their mechanistic profiles differ enough to warrant individual evaluation in clinical decision-making