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Furthermore, exosome-derived circTRPS1 from bladder cancer (BCa) cells could regulate intracellular ROS homeostasis and promote CD8 T cell depletion via the circTRPS1/miR141-3p/GLS1 axis [99]

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Blocking CXCR3 signaling using monoclonal antibodies resulted in worsened disease, which was accompanied by reduced recruitment of T cells, ILCs, and macrophages, and a marked increase in neutrophil infiltration

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