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Treatment was continued for 8 weeks during caging, and litter size was recorded

FT-IR spectroscopy analysis was carried out with a Bruker Tensor 27 Spectrometer using in the range of 4000 to 400 cm 1 at room temperature

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ALP exposure induced short-term increases in ERK1/2 signaling within the VTA-NAc pathway, and though speculative, repeated ALP may be sensitizing this neural system resulting in an enhancement of opioid reward