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Acknowledgments This article was supported by the Key Scientific Research Fund of the Hunan Provincial Department of Education (No.: 22A0262), the Scientific Research Project of the Hunan Provincial Health Commission (No.: 202203105682), the Hunan Traditional Chinese Medicine Research Fund (No.: D2022104), the Hunan Provincial Natural Science Foundation of China (No.: 2025JJ90060), the fifth batch of the 2022 National Advanced Training Program for Outstanding Clinical Talents in Traditional Chinese Medicine (Document No

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Mara Fosch et al., 2022