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First article was published in 2007, and on the other hand, several authors have recently carried out systematic reviews on the use of PEA in humans to treat or prevent chronic pain of different aetiologies, some of them very recent and of high quality (20)

Reported reactions included nausea, vomiting, chills, low blood pressure, breathing difficulty and hospitalization, with excessive endotoxin exposure identified as a concern

Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE / mice

Dinga R, Marquand AF, Veltman DJ, Beekman ATF, Schoevers RA, van Hemert AM, Penninx BWJH, Schmaal L (2018) Predicting the naturalistic course of depression from a wide range of clinical, psychological, and biological data: a machine learning approach

Genome-wide pleiotropy between Parkinson disease and autoimmune diseases