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Consistent with this finding, we observed higher expression of TGF and p-Smad2 in NP and L929 cocultures, but no expression of either was observed in NP and 293T cocultures (Supplementary Fig

SchutzerSEBodyBABoyleJBransonBMDattwylerRJFikrigEet al

However, it is unlikely that osmotic lysis has any significant role in normal red cell destruction because there is no site within the vascular compartment where the plasma is sufficiently hypotonic to bring lysis about

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