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doi: 10.1016/0024-3205(95)02082-T

Green Relief Health recommends 1-2 month breaks between extended courses to optimize receptor sensitivity and prevent tolerance development

0.277 between Pharmavista and MediQ and 0.131 for the three databases), echoing earlier findings by Amkreutz et al., with a concordance coefficient of 0.23 [95% CI 0.11, 0.35] between Pharmavista and MediQ for DDIs focusing on immunosuppressants (Shariff et al., 2021)