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It is not a replacement for prescribed mental health treatment, and severe depression should always be managed by a licensed clinician

Anecdotal reports from research settings suggest enhanced outcomes compared to single-agent use, though controlled comparative studies remain limited

Sikiric, P., Seiwerth, S., Grabarevic, Z., Rucman, R., Petek, M., Jagic, V., Turkovic, B., Rotkvic, I., Mise, S., Zoricic, I., Konjevoda, P., Perovic, D., Simicevic, V., Separovic, J., Hanzevacki, M., Ljubanovic, D., Artukovic, B., Bratulic, M., Tisljar, M., & Rekic, B

J Physiol (Paris) 1997

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