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To further confirm that the autophagic cell death of GABAergic neurons was also induced by sulindac in mice, haematoxylin/eosin (H&E) staining and Nissl staining were performed and revealed that sulindac administration for 1 month also resulted in significant neuronal cell death in mice at doses of 26 mg/kg, 52 mg/kg (human equivalent dose) and 104 mg/kg (Fig

Considering the critical role of methylation in sustaining the normal cell function and maintaining the various cellular processes, any alterations in SAMe metabolisms can bring profound influence in cell growth, differentiation and normal function

& Neely, G

The impact of the reaction pH on activity of A

Ammonia-lowering strategies for the treatment of hepatic encephalopathy