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PPIs block gastric H+K+-ATPase, which is responsible for pumping H+ ions from within gastric parietal cells into the gastric lumen, where they interact with Cl ions to form HCl

Thyroid stimulating hormone upregulates secretion of cathepsin B from thyroid epithelial cells

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Blocking the HGF/c-Met/mTOR signaling pathway by knocking down the expression of mTOR inhibits PNI of pancreatic cancer To further understand the role of mTOR in the progression of the HGF/c-Met pathway promoting PNI in pancreatic cancer, the lentiviral vector mTOR-shRNA was used to suppress mTOR expression in pancreatic cancer cell lines

smegmatis fails to divide normally in the presence of CB7620870, suggesting that long-term exposure to this drug perturbs bacterial cell division