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Studies indicate that when patients receive timely feedback on their condition and treatment efficacy, they typically exhibit higher compliance and a more positive outlook on their treatment [216,217,218]

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In addition, 38.1% of tumor growth was inhibited when treated with BRNPs individually, suggesting that BRNPs, as well as free bilirubins, also have inherent anticancer efficacy

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Risk factors for vitamin B12 include (13, 14): Plant exclusive dietary intake: As animal-derived foods are the primary source of vitamin B12, those following a plant-exclusive diet have a higher risk of vitamin B12 deficiency