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Transcription activator AP-1 (a heterodimer consisting of c-Fos and c-Jun) and Nrf2 are also redox-sensitive transcription factors, which are closely related to the pathogenesis of RA (214)

Renal histopathology The collected tissues were processed and sectioned at a thickness of 5 m and stained with trichrome masson [29]

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and caspase 3, pmTOR (S2448) and VDAC (1:1000, Cell Signaling Technology, Danvers, MA, USA) were included in the assay

Based on several human RCTs, melatonin is considered an effective intervention to resolve delirium, ameliorate respiratory stress (i.e., ARDS), and restore circadian balance in COVID and PASC patients 664,665,666