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Integration of HMC3 into three-dimensional tumor spheroids further enables modeling of microglial infiltration and nanoparticle-based drug delivery (339, 340)

Oxygen therapy was again tried when the U.S navy used hyperbaric oxygen to treat deep-sea divers having decompression sickness in the 1940s

This artificial sweetener-induced glucose intolerance was mediated by changes to the commensal microbiota, with contributions from diverse bacterial taxa, because treatment with broad spectrum antibiotics protected animals against glucose intolerance phenotype

45,46 A number of clinical trials have examined the effects of creatine supplementation on cognitive function in healthy adults of various ages and results have been mixed

As noted by Kraus et al., Nature Medicine , NNMT inhibition in white adipose tissue significantly increased energy expenditure and reduced fat mass in animal models without changes to diet or activity