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The pathological hallmarks of PD involve depletion of striatal dopamine and axonal degeneration associated with loss of the dopaminergic neurons

Glutathione is involved in metabolism of toxins and carcinogens, DNA synthesis and repair, protein and prostaglandin synthesis, amino acid transport, immune system function, prevention of oxidative cell damage, and enzyme activation

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Recent studies have emphasized the dysregulation of the Treg/Th17 axis in Hashimotos thyroiditis, with a shift toward proinflammatory Th17 responses (e.g., IL-17, IL-22) and reduced regulatory T cell activity