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However, the emergence of viral variants, particularly Omicron strains with more than 30 mutations in the spike protein, has diminished the efficacy of several marketed antibodies, driving the development of therapeutics with broader neutralizing capabilities 47

Gunnarsdottir S and Elfarra AA

The buffering genetic interaction revealed from our CRISPR screen 13 allowed further extending the finding by demonstrating a functional coordination of mitochondrial glutathione uptake (mediated by SLC25A39) and mitochondrial iron import (mediated by SLC25A37) in supporting OXPHOS

- One milligram of Dynabeads MyOne Streptavidin C1 magnetic beads typically binds more than 2,500 pmol free biotin, 400 pmol of biotinylated peptides, up to 20 g of biotinylated antibody, 20 g of biotinylated double-stranded DNA, or 500 pmol of biotinylated single-stranded oligonucleotides

J Biol Chem 277(32):2857228577