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To maximize and analyze differences among the five groups, partial least square-discriminant analysis (PLS-DA) was also performed

In SLE, nutritional therapy, which involves limiting the protein and carbohydrate intake as well as using nutritional supplements (such as vitamins, minerals, and polyphenols), is often considered a potential approach to managing inflammatory reactions ( 5.4 Application of immunomodulators Reducing the severity and maintenance of tissue homeostasis is the major goal in the treatment of SLE patients using various biological agents, immunosuppressants, glucocorticoids, etc

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The identified genes were not limited to those encoding metabolic enzymes, also genes encoding transporters and genes involved in cofactor synthesis were discovered

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