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This osteoporosis may be attributed to the intracellular accumulation of iron, which induces G1 cell cycle arrest in osteoblasts, accompanied by downregulation of Cyclin D1, Cyclin D3, CDK2, CDK6, and CDK6 expression, thereby suppressing osteoblast proliferation (Yuan et al., 2019)

Moreover, they had increased elasticity and smoothness over subjects treated with placebo lotion

Moreover, in a study carried out in vitro, rosuvastatin inhibited foam cell formation and stimulated ABCA1 and ABCG1 expression by promoting autophagy in macrophages (Zhang et al., 2021)