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doi:10.1177/2633494120913032 MedlinePlus

For example, p53 depletion can enhance cell proliferation and survival, disrupt apoptosis and increase genomic instability by altering the expression of REDD1, an mTOR suppressor

In contrast to their protein-bound counterpart, FAAs can interact with specific receptors present on a wide variety of cells in various parts of the body, including the intestines, where they can activate specific intracellular pathways and confer physiological effects (34, 48)

89 Resistance due to Inactivation by Glutathione or GSTs Intracellular inactivation of alkylating agents has been implicated in human tumor resistance