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Though it has not met the conventional structural endpoints needed for regulatory approval, SS-31 showed very promising visual signal effects in a specific subpopulation of patients with Geographic Atrophy (GA): Low Luminance Visual Acuity (LLVA): Patients showed significant improvement in reading ability in low light conditions

PKA and CREB phosphorylation are two EP2 receptor signaling pathways that are activated by PGE2 and inhibited by decursinol angelate

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Turk J Hematol

The immediate and delayed readings of the prick test and intradermoreaction test with Dermaheal LL were also negative