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They are all ubiquitous except -butyrobetaine hydroxylase is absent from cardiac and skeletal muscle

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

For instance, some cancer cells have overactive growth receptors on their surface, which targeted therapies can block, slowing down cancer growth

J Clin Oncol 22 : 36943699 Bianco A et al

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