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This has not been reproduced in studies with reliable effects, but it is considered an area that needs more attention

Thus, ferritin abundance controls ferroptosis sensitivity: ferritin raises the susceptibility to ferroptosis when unstable iron pools are limited because it promotes iron ion preservation

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Furthermore, C3 inhibitors such as the compstatin analog AMY-101, by blocking C3 convertase, reduced kidney damage and systemic inflammation in hemorrhagic shock models