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Holsteins are very adaptive to adverse environments and inclement weather conditions as well as the naturally most efficient milk producers among their class of dairy cattle

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1e and Supplementary Videos 2and 3) confirmed that ER vesiculation split the ER from the NE

Glucose-6-phosphate dehydrogenase (G6PD) is one of the key antioxidant enzymes, which reduces nicotinamide adenine dinucleotide phosphate (NADP+) to NADPH

Increased expression of glucose transporters (GLUT1/3) and hexokinase 2 (HK2), which are regulated by HIF-1 and HIF-2, supports glycolysis, even under hypoxic conditions