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(ii) However, further metabolic changes occur in the Mt-infected THP-1 cells at later time points

J Biol Chem 283:45434559 Chen C, Krausz KW, Shah YM, Idle JR, Gonzalez FJ (2009) Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity

Free Radic Res 41:12011211 Ursini F, Maiorino M, Brigelius-Flohe R, Aumann KD, Roveri A, Schomburg D, Flohe L (1995) Diversity of glutathione peroxidases

These processes facilitate the appearance of more leukocytes, which modify lipoproteins and transform them into atherosclerotic plaques and chronic inflammation