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A 2023 randomised study of 214 adults found only 0.9 lbs additional loss after three months compared to placebo not statistically significant

Masking Underlying Health Issues: While B complex supplements can help improve symptoms of B vitamin deficiency, they will not address the underlying cause of the deficiency

Semaglutide can reduce B12 absorption by slowing gastric transit, but not all patients develop deficiency

A patient whose BCBS plan limits mental health visits to 30 per year may have unlimited medical benefit coverage for the same provider's services when billed under HBAI codes with a physical health diagnosis

This needs further research and its unknown whether it was high levels of vitamin B12 causing the cancer or if the cancer caused high levels of vitamin B12