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Semaglutide works by slowing stomach emptying and reducing appetite through GLP-1 receptor activation, while glutathione functions as a cellular detoxifier

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This alleviates HIF-1-mediated inflammation and promotes the repolarization of macrophages toward the M2 phenotype (Shao et al., 2025), demonstrating that correcting specific mitochondrial metabolic pathways is a viable therapeutic strategy (Liu et al., 2025) (Table 2)

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Ferroptosis can activate antigen-presenting cells by releasing DAMP-related molecules, induce immune responses, and trigger anti-tumor immune memory through ICD