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In senescent cells, disrupting this interaction causes p53 to translocate to the mitochondria, triggering apoptotic cell death specifically in aged, dysfunctional cells while sparing healthy ones [1]

370 In addition, diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) can relieve the gut symptoms of patients with quiescent IBD, possibly reducing the fecal abundance of microbes and thereby regulating the immune response of the host

10.1016/j.bbi.2007.08.009 18

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Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: Results of the HGF-0205 trial