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They discovered that the binding of a peptide mimicking the MDM4 C-terminus tail to MDM2 impairs MDM2-mediated ubiquitination of p53 and promotes p53-dependent transcription and oncosuppressive activities [57]

Reconstituted peptide solutions that are contaminated with bacteria can cause skin infections that dramatically worsen eczema

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These resistant cells have also higher levels of FGF2 compared to the normal HUVAC, and following incubation with Bevacizumab, a further increase in FGF2 transcription and translation was observed alongside an increase in levels of FGFR1 and its phosphorylation