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Methods 2015 , 12 , 921924

viteae, T

Several electrostatically driven side-chain to side-chain contacts are observed, particularly involving the carboxyl groups of D650, E653, and E657 of BRD4 ET and the guanidino and ammonium moieties of R578, R573, and K568 of ASXL1 EBM , respectively, and the carboxyl group of E651 of BRD4 ET is likely engaged with the side chain amide nitrogen of Q575 of ASXL1 EBM