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Description

Disruption of the hexokinase-VDAC complex for tumor therapy

70 HMGR inhibitor statins reduced GPX4 expression in cancer cells, leading to elevated lipid peroxides and making cancer cells sensitive to ferroptosis

6 Clinical insights Clinical research on luteolin and its formulations has increasingly highlighted its potential therapeutic applications across diverse conditions, including cancer, neurological disorders, metabolic syndromes, and post-COVID complications (refer to Fig