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Furthermore, Cyn inhibits the activation of NF-B and microglia, thereby downregulating the proinflammatory cytokines in the hippocampus and reducing neuronal damage in CUMS-induced mice

GrimaldiL.CavallaroR

For example, the SPARC level increased in the skeletal muscles of young male subjects after 11 weeks of a strength-training program [21], and it transiently increased in the serum of young healthy men immediately after a single bout of cycling [22]

doi: 10.3389/fcell.2021.695900 63

Saenger P, Pescovitz OH, Bercu BB, Murray FT, Landy H, Brentzel J, O'Dea L, Hanson B, Howard C, Reiter EO, Geref International Study Group: Outcome of growth hormone therapy in children with growth hormone deficiency showing an inadequate response to growth hormone-releasing hormone