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Utilization of host-derived Glycans by intestinal Lactobacillus and Bifidobacterium species

The discrepancy between this study and the data herein may reflect the heterogeneous nature of CD and disease severity between the patient donors (the current study used monocytes from individuals with mild-to-moderate CD), the mechanisms of action of the various pro-death stimuli, or differences in apoptotic versus non-apoptotic death in macrophages

10.1016/j.celrep.2017.12.077 125 ThomasM

490 FBXW7, which catalyzes the degradation of the anti-apoptotic protein MCL1, plays a key role in myeloid cells and SLE progression